http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#Head http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://www.nanopub.org/nschema#hasAssertion http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#assertion http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://www.nanopub.org/nschema#hasProvenance http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#provenance http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://www.nanopub.org/nschema#hasPublicationInfo http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#pubinfo http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#assertion http://purl.obolibrary.org/obo/DOID_8469 https://w3id.org/biolink/vocab/category https://w3id.org/biolink/vocab/Disease http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://purl.obolibrary.org/obo/DOID_8469 http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate https://w3id.org/biolink/vocab/treats http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://identifiers.org/drugbank:DB00198 http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association http://www.w3.org/2000/01/rdf-schema#label tamiflu is an influenza neuraminidase inhibitor indicated for treatment of influenza in patients 1 year and older who have been symptomatic for no more than 2 days 1 1 prophylaxis of influenza in patients 1 year and older 1 2 important limitations of use efficacy not established in patients who begin therapy after 48 hours of symptoms 1 3 not a substitute for annual influenza vaccination 1 3 no evidence of efficacy for illness from agents other than influenza viruses types a and b 1 3 consider available information on influenza drug susceptibility patterns and treatment effects when deciding whether to use 1 3 tamiflu is indicated for the treatment of uncomplicated acute illness due to influenza infection in patients 1 year and older who have been symptomatic for no more than 2 days tamiflu is indicated for the prophylaxis of influenza in patients 1 year and older the following points should be considered before initiating treatment or prophylaxis with tamiflu efficacy of tamiflu in patients who begin treatment after 48 hours of symptoms has not been established tamiflu is not a substitute for early influenza vaccination on an annual basis as recommended by the centers for disease control and prevention advisory committee on immunization practices there is no evidence for efficacy of tamiflu in any illness caused by agents other than influenza viruses types a and b influenza viruses change over time emergence of resistance mutations could decrease drug effectiveness other factors for example changes in viral virulence might also diminish clinical benefit of antiviral drugs prescribers should consider available information on influenza drug susceptibility patterns and treatment effects when deciding whether to use tamiflu http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association https://w3id.org/biolink/vocab/association_type https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association https://w3id.org/biolink/vocab/provided_by https://w3id.org/um/NeuroDKG http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#association https://w3id.org/biolink/vocab/relation https://schema.org/TreatmentIndication https://identifiers.org/drugbank:DB00198 https://w3id.org/biolink/vocab/category https://w3id.org/biolink/vocab/Drug http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#provenance http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#assertion http://www.w3.org/ns/prov#wasAttributedTo https://orcid.org/0000-0002-1468-3557 http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#pubinfo http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#sig http://purl.org/nanopub/x/hasAlgorithm RSA http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#sig http://purl.org/nanopub/x/hasPublicKey MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#sig http://purl.org/nanopub/x/hasSignature VIHf9tXz8WA9BTy0XLhbMfU2CG/HwVbvrvJ5+65H11ewrqgMQ+r35/Ya7Ms80sZN2W6BeU0QrcojmKVV0DKTTHQLT6BszMDn0h+XidySoD7IR4Yvt1apj9L3ibH7y8tlstVpagWuz9aMJIY69vOwiUu6iihe8qWF43alBszBeQY= http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM#sig http://purl.org/nanopub/x/hasSignatureTarget http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://purl.org/dc/terms/created 2021-06-12T16:44:56.782+02:00 http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM http://purl.org/dc/terms/creator https://orcid.org/0000-0002-1468-3557 http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM http://purl.org/np/RAyIryxwdjDh1nppIOXe9YKv3OI9tkARZO-4_gLxK5aPM https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs