. . . . . . . "[Expression of a constitutively active mutant of G?(i2) stimulated myotube growth and differentiation, effects that required the transcription factor NFAT (nuclear factor of activated T cells) and protein kinase C. In addition, expression of the constitutively active G?(i2) mutant inhibited atrophy caused by the cachectic cytokine TNF? (tumor necrosis factor-?) by blocking an increase in the abundance of the mRNA encoding the E3 ubiquitin ligase MuRF1 (muscle ring finger 1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:11+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .