http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#Head
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.nanopub.org/nschema#hasAssertion
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#assertion
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.nanopub.org/nschema#hasProvenance
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#provenance
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.nanopub.org/nschema#hasPublicationInfo
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#pubInfo
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#assertion
http://identifiers.org/drugbank/DB01175
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
https://w3id.org/biolink/vocab/Drug
http://identifiers.org/drugbank/DB01175
http://www.w3.org/2000/01/rdf-schema#label
escitalopram
http://identifiers.org/drugbank/DB01175
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/Drug
http://purl.obolibrary.org/obo/MONDO_0008114
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
https://w3id.org/biolink/vocab/Disease
http://purl.obolibrary.org/obo/MONDO_0008114
http://www.w3.org/2000/01/rdf-schema#label
obsessive-compulsive disorder
http://purl.obolibrary.org/obo/MONDO_0008114
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/Disease
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
http://purl.obolibrary.org/obo/MONDO_0008114
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
https://w3id.org/biolink/vocab/treats
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
http://identifiers.org/drugbank/DB01175
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
http://www.w3.org/2000/01/rdf-schema#label
Escitalopram showed favorable pharmacokinetics and good tolerability. It is the most 5-HT-selective among SSRIs, with little or no affinity for other transmitter transporters or receptors [59]. Compared to other SSRIs, escitalopram may have weak or minimal interactions with the cytochrome P450 system [60, 61]. In a randomized, double-blind, placebo-controlled 24-week trial in OCD, escitalopram (20 mg/day) was associated with an increase in response rate compared to placebo after 12 weeks. Other placebo-controlled studies consistently showed escitalopram-related treatment response [25, 30]. 20 mg/day escitalopram has also been associated with better OCD symptom remission compared to 40 mg/day paroxetine or placebo at week 12 [30]. Three different escitalopram dosages (5, 10, and 20 mg/day) were compared with a fixed, 20 mg/day dose of paroxetine in a 12-week study, in which escitalopram showed both greater efficacy and better tolerability [62].
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
https://w3id.org/biolink/vocab/aggregator_knowledge_source
https://w3id.org/biolink/infores/knowledge-collaboratory
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/ChemicalToDiseaseOrPhenotypicFeatureAssociation
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
https://w3id.org/biolink/vocab/has_population_context
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#context
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
https://w3id.org/biolink/vocab/publications
http://www.ncbi.nlm.nih.gov/pubmed/30101713
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#association
https://w3id.org/biolink/vocab/relation
http://purl.obolibrary.org/obo/NCIT_C94303
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#context
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
https://w3id.org/biolink/vocab/Cohort
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#context
http://www.w3.org/2000/01/rdf-schema#label
adults
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#context
https://w3id.org/biolink/vocab/category
https://w3id.org/biolink/vocab/Cohort
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#provenance
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#assertion
http://www.w3.org/ns/prov#wasAttributedTo
https://orcid.org/0000-0002-7641-6446
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#pubInfo
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#sig
http://purl.org/nanopub/x/hasAlgorithm
RSA
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#sig
http://purl.org/nanopub/x/hasPublicKey
MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#sig
http://purl.org/nanopub/x/hasSignature
PVsL+yEE5Nsi+zVQtMT5N+DrHb4vbNHsbuhBPors+w1mbZIGCe7HmtvoJ3RQm4aUMwU14uisPy1PiKff49zxkKra6uoWE0biyS7WmZGj3Cr7gTPVKo+ebWAVKzy7F4rinpYucZOqDamc811jGl8vbOlH8vR6sqL5rnFYZYT/Glk=
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w#sig
http://purl.org/nanopub/x/hasSignatureTarget
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.w3.org/ns/prov#generatedAtTime
2022-09-16T11:53:46.825298
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
http://www.w3.org/ns/prov#wasAttributedTo
https://orcid.org/0000-0002-1501-1082
http://purl.org/np/RAwlUKOkdB0hlnEFIKDZZnj3Llnpi16vL85c7lnRd7t4w
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
https://w3id.org/biolink/vocab/
http://purl.org/pav/version
2.3.0