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1 1 the treatment of adult patients with unresectable well or moderately differentiated locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors gep nets to improve progression free survival 1 2 the treatment of adults with carcinoid syndrome when used it reduces the frequency of short acting somatostatin analog rescue therapy 1 3 somatuline depot is indicated for the long term treatment of acromegalic patients who have had an inadequate response to surgery and or radiotherapy or for whom surgery and or radiotherapy is not an option the goal of treatment in acromegaly is to reduce growth hormone gh and insulin growth factor 1 igf 1 levels to normal somatuline depot is indicated for the treatment of adult patients with unresectable well or moderately differentiated locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors gep nets to improve progression free survival somatuline depot is indicated for the treatment of adults with carcinoid syndrome 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