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[We used non-invasive optical imaging of firefly luciferase to repeatedly monitor, in living animals, the ability of sCAR-EGF (i) to 'transductionally untarget' systemically administered Ad.CMVfLuc, an adenovirus that constitutively expresses luciferase, from normal tissues and (ii) to 'transductionally redirect' adenovirus infection in mice to xenograft tumors that express elevated epidermal growth factor (EGF) receptor levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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