@prefix this: <http://purl.org/np/RAoMvSloXnVwg48KXkUWn_gb5depyi_b9CiNQZ-4Z4N_U> .
@prefix sub: <http://purl.org/np/RAoMvSloXnVwg48KXkUWn_gb5depyi_b9CiNQZ-4Z4N_U#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_0060318> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_0060318> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00755> ;
    a rdf:Statement ;
    rdfs:label "tretinoin capsules are indicated for the induction of remission in patients with acute promyelocytic leukemia apl french american british fab classification m3 including the m3 variant characterized by the presence of the t 15 17 translocation and or the presence of the pml rari gene who are refractory to or who have relapsed from anthracycline chemotherapy or for whom anthracycline based chemotherapy is contraindicated tretinoin capsules are for the induction of remission only the optimal consolidation or maintenance regimens have not been defined but all patients should receive an accepted form of remission consolidation and or maintenance therapy for apl after completion of induction therapy with tretinoin capsules" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation nkg:SymptomaticReliefIndication .
  <https://identifiers.org/drugbank:DB00755> bl:category bl:Drug .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
    npx:hasSignature "Ez+ST6P2RgmtI+Jl9MRmQglECNFciLbcNe9fxg4alaeJjPYXA+QPmIVY+zdT3zyewEOLvF4xFhMz+7wK7xAsU9La9qSscuarl46oIDltC0DMmUrE2aSY0T6qx9rYEsfmVdmpSkI7ZLamCxQyJwbE9lqbQaigUtak20+1//63SRQ=" ;
    npx:hasSignatureTarget this: .
  this: dct:created "2021-06-12T16:32:41.896+02:00"^^xsd:dateTime ;
    dct:creator orcid:0000-0002-1468-3557 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}