@prefix this: <http://purl.org/np/RAnS8enFCRKPFV9sKBO8nNL7HRpQDNSp90h_5XUWcUZ24> .
@prefix sub: <http://purl.org/np/RAnS8enFCRKPFV9sKBO8nNL7HRpQDNSp90h_5XUWcUZ24#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0013600> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0013600>;
    rdf:predicate bl:treats;
    rdf:subject <https://go.drugbank.com/drugs/DB01224>;
    a rdf:Statement;
    rdfs:label "However, studies have demonstrated that of all the antipsychotics, quetiapine is the most frequently used off-label to treat conditions such as insomnia and post-trau- matic stress disorder (McKean and Monasterio, 2012) and has been flagged as the most concerning in terms of lack of evidence to support these indications and potential to cause harm (Walton et al., 2008).";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:has_population_context sub:cohort;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/28758432/>;
    bl:relation nkg:OffLabelIndication .
  
  sub:cohort rdfs:label "Adults";
    bl:category bl:Cohort .
  
  <https://go.drugbank.com/drugs/DB01224> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "ESZmy5hr3EmkFRnZtgdCud5vaJ4PGaHYPjcf4dzQlvMIAent1hbBIanqdb1rRos5emQGkIaEYcK+ateH4SphuwEfS80zr1T2u+kKsKgopKE4/qX7ySuBsy7owbBWb4zzDiTmB63RHywBtMCFHBUKNPTMSI1pyk7fQnoLVx4W4G8=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-05-25T10:42:49.508+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-7641-6446;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg> .
}