@prefix this: <http://purl.org/np/RAnOEjxnegEgcmFPfhkvSh87z2In5guTGtAlZ8pSDhLu0> .
@prefix sub: <http://purl.org/np/RAnOEjxnegEgcmFPfhkvSh87z2In5guTGtAlZ8pSDhLu0#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_12802> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_12802>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/drugbank:DB00090>;
    a rdf:Statement;
    rdfs:label "aldurazyme r aldurazyme has been shown to improve pulmonary function and walking capacity aldurazyme has not been evaluated for effects on the central nervous system manifestations of the disorder aldurazyme is a hydrolytic lysosomal glycosaminoglycan gag specific enzyme indicated for patients with hurler and hurler scheie forms of mucopolysaccharidosis i mps i and for patients with the scheie form who have moderate to severe symptoms the risks and benefits of treating mildly affected patients with the scheie form have not been established aldurazyme has been shown to improve pulmonary function and walking capacity aldurazyme has not been evaluated for effects on the central nervous system manifestations of the disorder 1";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:relation schema:TreatmentIndication .
  
  <https://identifiers.org/drugbank:DB00090> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "WzyKVe970wRVQ/9Iiyx2IXoarZTJMpm9yrlHAEwVqpUGMd/qO3FxcPsvOUSXgwqql3UsEpcYRwmc8Frf42yjUSSzIqRXQmLyNFVqu977cp3tIrhSBsgJ6b3dQkMVJeI2KABB/AgXtitPmdD/+ZEZYHWpV95wB1eAnaVETKfJLKQ=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-06-12T13:17:06.873+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}