. . . . . . . "[In this study, we demonstrate that Fc?RIIB(-/-) mice generated by gene targeting in B6-derived ES cells (Fc?RIIB(B6)(-/-)), lacking the 129-derived flanking Sle16 region, exhibit a hyperactive phenotype but fail to develop lupus indicating that in Fc?RIIB(129)(-/-) mice, not Fc?RIIB deficiency but epistatic interactions between the C57BL/6 genome and the 129-derived Fc?r2b flanking region cause loss of tolerance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:12:40+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .