. . . . . "Doxepin" . . . "sleep disorder" . . . . . . "Among TCAs, doxepin (sinequan) appears to be best suited for managing insomnia in healthy adults. Doxepin works as a selective antagonist to H(1) receptors, which promote the initiation and maintenance of sleep (Owen, 2009) (Table 2). Ultra-low doses of this drug (< 6 mg per day) significantly improve and sustain both maintenance and duration of sleep (Rojas-Fernandez and Chen, 2014; Weber et al., 2010). Another frequently prescribed TCA is amitriptyline, which as a long-term option is found to be effective for patients with ongoing sleep problems (Everitt et al., 2014; Pagel and Parnes, 2001)." . . . . . . . "Adults" . . . "RSA" . "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" . "I7oNLKBrVAdqz8XoJB5x9LtTz+pg9LieuAqSpqupFhlxtf39tecKUZbFzXOSApcmR8KqVV09IIf4p9slvReCsNL1iC9b9vK+IdtbfMMHnwUedhA5iEPKjZ61CdBCcAg4f1ojIVfv5e/9IoZNcL1YMVv50kqCTRl2GaDaei+l54c=" . . "2022-09-16T11:49:06.644774"^^ . . . "2.3.0" .