@prefix this: <http://purl.org/np/RAkYw0G19QAn2E0EfkUxj7gZA5EY1V3G58YWo8Cqs12Xs> .
@prefix sub: <http://purl.org/np/RAkYw0G19QAn2E0EfkUxj7gZA5EY1V3G58YWo8Cqs12Xs#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_8442> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_8442>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/drugbank:DB00813>;
    a rdf:Statement;
    rdfs:label "\"Fentanyl transdermal system is contraindicated in the following patients and situations:   in patients who are not opioid-tolerant.            in patients who have or are suspected of having paralytic ileus. in patients with known hypersensitivity to fentanyl or any components of the transdermal system. Severe hypersensitivity reactions, including anaphylaxis have been observed with fentanyl transdermal system  [see   Adverse Reactions (6.2)   Opioid non-tolerant patients. ( 4 Acute or intermittent pain, postoperative pain, mild pain. ( 4 Respiratory compromise, acute or severe asthma. ( 4 Paralytic ileus. ( 4 Known hypersensitivity to fentanyl or any of the components of the transdermal system. ( 4\"";
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:relation schema:MedicalContraindication .
  
  <https://identifiers.org/drugbank:DB00813> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "L+DsiRmrejWn+UBBWh73mSfjeL9hKMhoKCz3v1nCNJfNbnquvKTJdae27NEBTpx9IP0VKxmigV8l9KGZIRrdDh/SLzFDsZsMX6dlTmF4BjgMK4fm56cSbhVbRQmhilqnk96Lt8bBaGXqs4mItHXA/btjtL34PrxKSFGYmgoEMNo=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-08-23T12:54:34.298+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}