@prefix this: <http://purl.org/np/RAeMUX2d_wfvZinhs9mygYktXJofHWbGeuYQXvWA029oI> .
@prefix sub: <http://purl.org/np/RAeMUX2d_wfvZinhs9mygYktXJofHWbGeuYQXvWA029oI#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:association rdf:object <https://identifiers.org/MONDO:0021668>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/CHEBI:7859>;
    a rdf:Statement;
    rdfs:label "OXYCODONE HCl EXTENDED-RELEASE TABLETS are indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate in: adults and Opioid-tolerant pediatric patients 11 years of age and older who are already receiving and tolerate a minimum daily opioid dose of at least 20 mg oxycodone orally or its equivalent";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:has_population_context sub:cohort;
    bl:provided_by "NeuroDKG";
    bl:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c5b52ff1-21a6-4d28-9982-55b4ac195fac>;
    bl:relation schema:TreatmentIndication .
  
  sub:cohort rdfs:label "adults and Opioid-tolerant pediatric patients 11 years of age and older";
    schema:requiredMinAge "11";
    bl:category bl:Cohort .
  
  <https://identifiers.org/CHEBI:7859> bl:category bl:Drug .
  
  <https://identifiers.org/MONDO:0021668> bl:category bl:Disease .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "a/YX5Xu+VK7dsk/SEU6g5EYssQoA4ZQOLuJ4y8cVwIe4JzIFvEGZChhesjhZNejyjapuDLVCFiEgc1Syp/nfPiCVj7W3OJSR1Imap0Xe84J8ylxy7lPYq5a+TXYhB6JZ1bm9Jyp60YQqygXioGFrlzo4odl4T1Rijj0D3e8cCSg=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-03-23T20:29:33.137+01:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RA59AEpaWRaR9sjdA0-n4zaQWdiZ6--iGafMrjrDAOheI> .
}