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[The findings suggest the following profound disturbances in the hypothalamic-pituitary-thyroid axis: 1) a 'euthyroid sick syndrome,' evidenced by low levels of triiodothyronine (T3), high levels of reverse T3, and normal levels of thyroxine (T4) (this syndrome implies a decreased 5'-deiodination of T4 to T3 and of reverse T3 to its lesser iodinated metabolites), 2) an increased binding capacity for thyroid hormones, evidenced by a decreased T3-uptake value and an increased level of T4-binding globulin, and 3) thyroid-stimulating hormone (TSH) blunting in 31% of patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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