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[Our results in estrogen-unresponsive fibroblasts, ribosomal S6 kinase 2 kinase (RSK2) knockout cells, and estrogen receptor (ER)-deficient breast tumor cells show that kurarinone can inhibit tumor cell proliferation and selectively block nuclear NF?B transactivation of specific target genes such as IL6, cyclin D1, SOD2 but not TNFAIP2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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