@prefix this: <http://purl.org/np/RAc2TaEMQQYPM_U-iJzSu5cUH1m3fblXXfIP3oEkjOFyA> .
@prefix sub: <http://purl.org/np/RAc2TaEMQQYPM_U-iJzSu5cUH1m3fblXXfIP3oEkjOFyA#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  mesh:C072778 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "hypertensive";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  umls:C0264714 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "acute heart failure";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  umls:C0264719 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "acute congestive heart failure";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  umls:C1299487 a biolink:OrganismTaxon;
    rdfs:label "patients";
    biolink:category biolink:OrganismTaxon .
  
  <http://purl.obolibrary.org/obo/CHEBI_7596> a biolink:ChemicalEntity;
    rdfs:label "Nitroprusside";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/NCIT_C26791> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "bleeding";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:object mesh:C072778;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_7596>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
  
  sub:_2 rdf:object <http://purl.obolibrary.org/obo/NCIT_C26791>;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_7596>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
  
  sub:_3 rdf:object umls:C0264719;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_7596>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
  
  sub:_4 rdf:object umls:C0264714;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_7596>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
  
  sub:_5 rdf:object <http://purl.obolibrary.org/obo/NCIT_C26791>;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_7596>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94b996dc-ddc4-41ce-9a9f-3d91cb187473> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-13T12:52:04.510950"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Nitroprusside is indicated for immediate reduction of blood pressure of patients in hypertensive crises, reduce bleeding during surgery, and for the treatment of acute congestive heart failure. It is also indicated to reduce bleeding in surgery and reduce blood pressure during the procedure of blood surgery. It was also indicated for the reduction of bleeding during the surgery of patients with severe blood pressure and for acute heart failure patients." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "HJz33s/vjSWpSUt849g6T5f9gsWpQGVetsEV2uoDAaRZfGc65MXlUZYjs7qdV6xaocdl9Gn+kVtazgOtXkvLKFkbaH2vXWgpZRQ0R14uXgKmx2qfvDNqyhnK9WEl8c2adaCYhDwpAtqFoYa7pUZAw3TJc/iwCq0rpRvDwSJ5Qvd0kzHRjAeROHJXas09KKEtH7woIXmMFi/mz5a24H48G9WXnoL35Ur7ME+G9EfHsEqcdmrFJXdS3Agfk4J3+coLCbLUKYnLIausxQhH7GpNemNphC8tHJI9GemO3VpyQlGwYWaNAkud4Gigim2EnoOSGzg2dVvSDcobryCfwbLgkg==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-13T12:52:04.510950"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}