. . . . . "Amitriptyline" . . . "sleep disorder" . . . . . . "Among TCAs, doxepin (sinequan) appears to be best suited for managing insomnia in healthy adults. Doxepin works as a selective antagonist to H(1) receptors, which promote the initiation and maintenance of sleep (Owen, 2009) (Table 2). Ultra-low doses of this drug (< 6 mg per day) significantly improve and sustain both maintenance and duration of sleep (Rojas-Fernandez and Chen, 2014; Weber et al., 2010). Another frequently prescribed TCA is amitriptyline, which as a long-term option is found to be effective for patients with ongoing sleep problems (Everitt et al., 2014; Pagel and Parnes, 2001)." . . . . . . . "Adults" . . . "RSA" . "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" . "kOxpJ0a1ll+DkZ5RdcoknJfvuhEGsmNc4LggjXp8a1SwlMR9VQUiM8GU3r//BvCSkg2v9AOzFNRVJdYscxiX77JK5zuAw7d3QcHbsMi5VoG9zFqXoEuwCBXerRUl75nvVIfK5/FMxbf2SZxmUVM6xuz6DdVg2F6g7gTZkDKYzYU=" . . "2022-09-16T11:49:04.738316"^^ . . . "2.3.0" .