@prefix dc: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix this: <http://purl.org/np/RAb9vwGZDu9VKqn3XcvwGOdAvVNB0CDUvnSPhjkwsQ_tk> .
@prefix sub: <http://purl.org/np/RAb9vwGZDu9VKqn3XcvwGOdAvVNB0CDUvnSPhjkwsQ_tk#> .
@prefix has-source: <http://semanticscience.org/resource/SIO_000253> .
@prefix wp: <http://vocabularies.wikipathways.org/wp#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix wd: <https://www.wikidata.org/entity/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pmid: <http://identifiers.org/pubmed/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
sub:head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:publicationInfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://identifiers.org/uniprot/P16104> dc:isPartOf <http://identifiers.org/wikipathways/WP3305> , <http://identifiers.org/wikipathways/WP3312> , <http://identifiers.org/wikipathways/WP3339> , <http://identifiers.org/wikipathways/WP3359> , <http://identifiers.org/wikipathways/WP3364> , <http://identifiers.org/wikipathways/WP3397> , <http://identifiers.org/wikipathways/WP3404> , <http://identifiers.org/wikipathways/WP3543> , <http://identifiers.org/wikipathways/WP3547> , <http://identifiers.org/wikipathways/WP3550> , <http://identifiers.org/wikipathways/WP3565> , <http://identifiers.org/wikipathways/WP3567> , <http://identifiers.org/wikipathways/WP3571> , <http://identifiers.org/wikipathways/WP3801> , <http://identifiers.org/wikipathways/WP3813> , <http://identifiers.org/wikipathways/WP3819> , <http://identifiers.org/wikipathways/WP3959> ;
    wp:organismName "Homo sapiens" ;
    a wp:Protein .
  <http://identifiers.org/wikipathways/WP3305> wp:pathwayOntologyTag obo:PW_0000004 .
  <http://identifiers.org/wikipathways/WP3312> wp:pathwayOntologyTag obo:PW_0000004 .
  <http://identifiers.org/wikipathways/WP3339> wp:pathwayOntologyTag obo:PW_0000008 .
  <http://identifiers.org/wikipathways/WP3359> wp:pathwayOntologyTag obo:PW_0000085 .
  <http://identifiers.org/wikipathways/WP3364> wp:pathwayOntologyTag obo:PW_0000004 .
  <http://identifiers.org/wikipathways/WP3397> wp:pathwayOntologyTag obo:PW_0000003 .
  <http://identifiers.org/wikipathways/WP3404> wp:pathwayOntologyTag obo:PW_0000004 , obo:PW_0000378 .
  <http://identifiers.org/wikipathways/WP3543> wp:pathwayOntologyTag obo:PW_0001360 .
  <http://identifiers.org/wikipathways/WP3547> wp:pathwayOntologyTag obo:PW_0001756 .
  <http://identifiers.org/wikipathways/WP3550> wp:pathwayOntologyTag obo:PW_0000004 , obo:PW_0000203 .
  <http://identifiers.org/wikipathways/WP3565> wp:pathwayOntologyTag obo:PW_0001360 .
  <http://identifiers.org/wikipathways/WP3567> wp:pathwayOntologyTag obo:PW_0000099 .
  <http://identifiers.org/wikipathways/WP3571> wp:pathwayOntologyTag obo:PW_0000085 .
  <http://identifiers.org/wikipathways/WP3801> wp:pathwayOntologyTag obo:PW_0000100 .
  <http://identifiers.org/wikipathways/WP3813> wp:pathwayOntologyTag obo:PW_0000004 .
  <http://identifiers.org/wikipathways/WP3819> wp:pathwayOntologyTag obo:PW_0000100 , obo:PW_0001334 .
  <http://identifiers.org/wikipathways/WP3959> wp:pathwayOntologyTag obo:PW_0000085 , obo:PW_0000667 , obo:PW_0001559 .
}
sub:provenance {
  <http://identifiers.org/wikipathways/WP3305_r103040> dce:title "NoRC negatively regulates rRNA expression"@en .
  <http://identifiers.org/wikipathways/WP3312_r101523> dce:title "PRC2 methylates histones and DNA"@en .
  <http://identifiers.org/wikipathways/WP3339_r101086> dce:title "TCF dependent signaling in response to WNT"@en .
  <http://identifiers.org/wikipathways/WP3359_r101371> dce:title "DNA methylation"@en .
  <http://identifiers.org/wikipathways/WP3364_r101473> dce:title "SIRT1 negatively regulates rRNA expression"@en .
  <http://identifiers.org/wikipathways/WP3397_r101273> dce:title "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"@en .
  <http://identifiers.org/wikipathways/WP3404_r101429> dce:title "Oxidative Stress Induced Senescence"@en .
  <http://identifiers.org/wikipathways/WP3543_r101474> dce:title "DNA Double Strand Break Response"@en .
  <http://identifiers.org/wikipathways/WP3547_r101438> dce:title "Amyloid fiber formation"@en .
  <http://identifiers.org/wikipathways/WP3550_r101358> dce:title "Nonhomologous End-Joining (NHEJ)"@en .
  <http://identifiers.org/wikipathways/WP3565_r101425> dce:title "DNA Damage/Telomere Stress Induced Senescence"@en .
  <http://identifiers.org/wikipathways/WP3567_r101343> dce:title "HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)"@en .
  <http://identifiers.org/wikipathways/WP3571_r101543> dce:title "Gene Silencing by RNA"@en .
  <http://identifiers.org/wikipathways/WP3801_r101392> dce:title "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"@en .
  <http://identifiers.org/wikipathways/WP3813_r101509> dce:title "Activation of anterior HOX genes in hindbrain development during early embryogenesis"@en .
  <http://identifiers.org/wikipathways/WP3819_r101276> dce:title "B-WICH complex positively regulates rRNA expression"@en .
  <http://identifiers.org/wikipathways/WP3959_r101991> dce:title "DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM"@en .
  sub:assertion has-source: pmid:12963833 , pmid:17622968 , pmid:18804552 , pmid:19707781 , pmid:20493860 , pmid:22704343 , <http://identifiers.org/wikipathways/WP3305_r103040> , <http://identifiers.org/wikipathways/WP3312_r101523> , <http://identifiers.org/wikipathways/WP3339_r101086> , <http://identifiers.org/wikipathways/WP3359_r101371> , <http://identifiers.org/wikipathways/WP3364_r101473> , <http://identifiers.org/wikipathways/WP3397_r101273> , <http://identifiers.org/wikipathways/WP3404_r101429> , <http://identifiers.org/wikipathways/WP3543_r101474> , <http://identifiers.org/wikipathways/WP3547_r101438> , <http://identifiers.org/wikipathways/WP3550_r101358> , <http://identifiers.org/wikipathways/WP3565_r101425> , <http://identifiers.org/wikipathways/WP3567_r101343> , <http://identifiers.org/wikipathways/WP3571_r101543> , <http://identifiers.org/wikipathways/WP3801_r101392> , <http://identifiers.org/wikipathways/WP3813_r101509> , <http://identifiers.org/wikipathways/WP3819_r101276> , <http://identifiers.org/wikipathways/WP3959_r101991> .
}
sub:publicationInfo {
  sub:activity a prov:Activity ;
    prov:atLocation wd:Q1137652 ;
    prov:used <https://github.com/wikipathways/nanopublications> .
  this: dc:created "2019-03-17T12:10:18.442+01:00"^^xsd:dateTime ;
    dc:rights <http://creativecommons.org/publicdomain/zero/1.0/> ;
    npx:supersedes <http://purl.org/np/RAkOWXbNdyA8flgYs5c3MPMjcsxN8kEHUP07OQ3Y5lcvo> ;
    prov:wasDerivedFrom <http://identifiers.org/wikipathways/WP3305_r103040> , <http://identifiers.org/wikipathways/WP3312_r101523> , <http://identifiers.org/wikipathways/WP3339_r101086> , <http://identifiers.org/wikipathways/WP3359_r101371> , <http://identifiers.org/wikipathways/WP3364_r101473> , <http://identifiers.org/wikipathways/WP3397_r101273> , <http://identifiers.org/wikipathways/WP3404_r101429> , <http://identifiers.org/wikipathways/WP3543_r101474> , <http://identifiers.org/wikipathways/WP3547_r101438> , <http://identifiers.org/wikipathways/WP3550_r101358> , <http://identifiers.org/wikipathways/WP3565_r101425> , <http://identifiers.org/wikipathways/WP3567_r101343> , <http://identifiers.org/wikipathways/WP3571_r101543> , <http://identifiers.org/wikipathways/WP3801_r101392> , <http://identifiers.org/wikipathways/WP3813_r101509> , <http://identifiers.org/wikipathways/WP3819_r101276> , <http://identifiers.org/wikipathways/WP3959_r101991> ;
    prov:wasGeneratedBy sub:activity .
}