. . . . . . . "[the Ile359Thr mutation affects anticoagulation by 1) impeding the APC-mediated down-regulation of FVa and 2) by being a poor APC cofactor for the down-regulation of FVIIIa/findings explain the association of this mutation with thrombosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2009-03-31"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:12:35+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .