sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_1040> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_1040> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB01073> ;
    a rdf:Statement ;
    rdfs:label "fludarabine phosphate injection is a nucleotide metabolic inhibitor indicated for the treatment of adult patients with b cell chronic lymphocytic leukemia cll who have not responded to or whose disease has progressed during treatment with at least one standard alkylating agent containing regimen benefit in treatment naive or non refractory cll patients is not established 1 1 important limitations fludarabine phosphate should not be used in patients with severe renal impairment creatinine clearance less than 3 ml min 1 73 m 2 5 7 fludarabine phosphate injection is indicated for the treatment of adult patients with b cell chronic lymphocytic leukemia cll who have not responded to or whose disease has progressed during treatment with at least one standard alkylating agent containing regimen the safety and effectiveness of fludarabine phosphate injection in previously untreated or non refractory patients with cll have not been established fludarabine phosphate injection should not be used in patients with severe renal impairment creatinine clearance less than 3 ml min 1 73 m 2 see warnings and precautions 5 7" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB01073> bl:category bl:Drug .
}