[ { "@graph" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#pubinfo" } ] } ], "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#Head" }, { "@graph" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#assertion", "@type" : [ "https://w3id.org/np/o/ntemplate/AssertionTemplate" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Defining a drug indication with its medical context" } ], "https://w3id.org/np/o/ntemplate/hasStatement" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st00" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st01" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st02" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st03" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st04" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st05" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st06" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st07" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st08" }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st09" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#audienceType", "@type" : [ "https://w3id.org/np/o/ntemplate/LiteralPlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "has the target group (eg. adult, pregnant)" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#condition", "@type" : [ "https://w3id.org/np/o/ntemplate/GuidedChoicePlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "define the condition for target population using DOID" } ], "https://w3id.org/np/o/ntemplate/possibleValuesFromApi" : [ { "@value" : "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#disease", "@type" : [ "https://w3id.org/np/o/ntemplate/GuidedChoicePlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "has disease using DOID" } ], "https://w3id.org/np/o/ntemplate/possibleValuesFromApi" : [ { "@value" : "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#drug", "@type" : [ "https://w3id.org/np/o/ntemplate/UriPlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "add a Drugbank identifier here (e.g. DB00295)" } ], "https://w3id.org/np/o/ntemplate/hasPrefix" : [ { "@value" : "http://identifiers.org/drugbank/" } ], "https://w3id.org/np/o/ntemplate/hasPrefixLabel" : [ { "@value" : " has the drug" } ], "https://w3id.org/np/o/ntemplate/hasRegex" : [ { "@value" : "[DB]\\d{5}" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#indi_type", "@type" : [ "https://w3id.org/np/o/ntemplate/GuidedChoicePlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "add the indication type for medical therapy" } ], "https://w3id.org/np/o/ntemplate/possibleValue" : [ { "@id" : "https://schema.org/ApprovedIndication" }, { "@id" : "https://schema.org/PreventionIndication" }, { "@id" : "https://schema.org/TreatmentIndication" }, { "@id" : "https://w3id.org/neurodkg/AdjunctiveTherapy" }, { "@id" : "https://w3id.org/neurodkg/SymptomaticReliefIndication" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#maxAge", "@type" : [ "https://w3id.org/np/o/ntemplate/LiteralPlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Audiences defined by a person's maximum age." } ], "https://w3id.org/np/o/ntemplate/hasRegex" : [ { "@value" : "[0-9]*" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy", "@type" : [ "https://w3id.org/np/o/ntemplate/LocalResource" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "This medical therapy " } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#minAge", "@type" : [ "https://w3id.org/np/o/ntemplate/LiteralPlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Audiences defined by a person's minimum age." } ], "https://w3id.org/np/o/ntemplate/hasRegex" : [ { "@value" : "[0-9]*" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#quotedtext", "@type" : [ "https://w3id.org/np/o/ntemplate/LiteralPlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "add a quote here" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st00", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#quotedtext" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "http://www.w3.org/ns/prov#quotedText" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "1" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st01", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#drug" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/drug" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "2" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st02", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/possibleTreatment" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#disease" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "3" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st03", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#indi_type" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://w3id.org/neurodkg/indicationType" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "4" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st04", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/targtePopulation" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#medtherapy" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "5" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st05", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement", "https://w3id.org/np/o/ntemplate/OptionalStatement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#audienceType" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/audienceType" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "6" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st06", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement", "https://w3id.org/np/o/ntemplate/OptionalStatement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#minAge" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/requiredMinAge" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "7" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st07", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement", "https://w3id.org/np/o/ntemplate/OptionalStatement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#maxAge" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/requiredMaxAge" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "8" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st08", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement", "https://w3id.org/np/o/ntemplate/OptionalStatement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#condition" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://schema.org/healthCondition" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "9" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#st09", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement", "https://w3id.org/np/o/ntemplate/OptionalStatement" ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#symptom" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "https://w3id.org/neurodkg/hasSymptom" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop" } ], "https://w3id.org/np/o/ntemplate/statementOrder" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#integer", "@value" : "10" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#symptom", "@type" : [ "https://w3id.org/np/o/ntemplate/GuidedChoicePlaceholder" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "target biomedical entity from Translator NameResolution API" } ], "https://w3id.org/np/o/ntemplate/possibleValuesFromApi" : [ { "@value" : "https://name-resolution-sri.renci.org/lookup?limit=10&string=" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#targetpop", "@type" : [ "https://w3id.org/np/o/ntemplate/LocalResource" ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "has the target population" } ] }, { "@id" : "http://www.w3.org/ns/prov#quotedText", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "claims" } ] }, { "@id" : "https://schema.org/ApprovedIndication", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "An indication for a medical therapy that has been formally specified or approved by a regulatory body." } ] }, { "@id" : "https://schema.org/PreventionIndication", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "An indication for preventing an underlying condition, symptom, etc." } ] }, { "@id" : "https://schema.org/TreatmentIndication", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "An indication for treating an underlying condition." } ] }, { "@id" : "https://w3id.org/neurodkg/SymptomaticReliefIndication", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "An indication for only managing the symptoms of the condition" } ] } ], "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#assertion" }, { "@graph" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#assertion", "http://www.w3.org/ns/prov#wasAttributedTo" : [ { "@id" : "https://orcid.org/0000-0001-7769-4272" } ] } ], "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#provenance" }, { "@graph" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2020-12-07T18:00:00.000+01:00" } ], "http://purl.org/dc/terms/creator" : [ { "@id" : "https://orcid.org/0000-0001-7769-4272" } ], "http://purl.org/nanopub/x/supercedes" : [ { "@id" : "http://purl.org/np/RAskqjj-YM6iTe-EhzxoSiVC-b9awUfI1y-uQE2q0ZEVI" } ] }, { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#sig", "http://purl.org/nanopub/x/hasAlgorithm" : [ { "@value" : "RSA" } ], "http://purl.org/nanopub/x/hasPublicKey" : [ { "@value" : "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCOqbrPT5RmzxsvRXGHZSAXPzeRLt9ogiosL3tcPKC0g5J8B1577lnJ3oVKSfD80lgPJdr9K671RazGL/mkZ/yu/uCNqne07Q9jd6OIAEi3fldiVfGK8ZDh43rGWRuG+BlvbZ1lZRFrWsURTKTpMgh0C6vJFRIMkWH6ImbZC5JbbQIDAQAB" } ], "http://purl.org/nanopub/x/hasSignature" : [ { "@value" : "Q2mthgg7SLfv0OKnEKD43jst9EfVJqRvfEq3IVMvg+8Ru8hdYeoR/oppDH9yBAlQLybryXoBt7zI+NSbuS1ZEu5sp/3H/UfkU7vbmS+P/eYLY3Pt8TBDkObPJDb5drnC/PXjakY/NwtP4DoiaGDKU84MTaOkei3cqbCfO2bhpOY=" } ], "http://purl.org/nanopub/x/hasSignatureTarget" : [ { "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk" } ] } ], "@id" : "http://purl.org/np/RARBFKSjSb07s9AkXybAc937ia55iC2CAJrhrhQ7NDgJk#pubinfo" } ]