@prefix this: <http://purl.org/np/RALyJT2J_fRiVPvIwjPUxMlZle5hQFosiDC5aAqJ9vsHI> .
@prefix sub: <http://purl.org/np/RALyJT2J_fRiVPvIwjPUxMlZle5hQFosiDC5aAqJ9vsHI#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://identifiers.org/pubchem.compound/156391> a biolink:ChemicalEntity;
    rdfs:label "Naproxen";
    biolink:category biolink:ChemicalEntity .
  
  umls:C0149896 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "acute gout", "acute. gouty arthritis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  umls:C3532591 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "musculoskeletal inflammation";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0002471> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "bursitis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0004857> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "tendinitis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005178> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "osteoarthritis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005306> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "ankylosing spondylitis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0008383> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "rheumatoid arthritis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0018456> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "polyarticular juvenile idiopathic arthritis";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0021668> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "pain";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/NCIT_C143423> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "dysmenorrhea";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_10 rdf:object <http://purl.obolibrary.org/obo/MONDO_0021668>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_11 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005306>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_12 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005178>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_13 rdf:object <http://purl.obolibrary.org/obo/MONDO_0018456>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_2 rdf:object <http://purl.obolibrary.org/obo/MONDO_0008383>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_3 rdf:object <http://purl.obolibrary.org/obo/MONDO_0002471>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_4 rdf:object umls:C0149896;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_5 rdf:object umls:C3532591;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_6 rdf:object <file:///app/osteoarchritis>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_7 rdf:object umls:C0149896;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_8 rdf:object <http://purl.obolibrary.org/obo/NCIT_C143423>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
  
  sub:_9 rdf:object <http://purl.obolibrary.org/obo/MONDO_0004857>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/156391>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef78ff05-8e0f-463a-88cd-ca9a01aed76a> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-11T07:46:27.143757"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Naproxen is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and for the relief of mild to moderate pain. Further, it is first-line therapy for osteoarchritis, acute. gouty arthritis, dysmen. arthritis, and musculoskeletal inflammation and pain." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "Rdhday5gqH0uxhy7U82mJmN/NzFj0ZGdYIq5Yfqe/1TwlpkoldWlAk6rArrOWZleP+JAWovPXL+KHxFx8Y+tfPZvlX2RilRohNhxhkmLuUo3RO0xxOgPz8Va9QvvdXRaPOKLd3m0IT0ue9yE1Gelx2EMZ2DOut0RO3Sk4L3JmhuL4WcXG6+ew+b5YS7rtVKkPo60WFTHD7iTL5jS3LKFIxgrcQpFfdcPO7P4Z6NA4J8TquZ04fbKdVJ3YdGXpHY0UMHxqoqCFNmCrtpDgmylfGoNk0ZfGbaHTsA4ZLOOQhA2NAVzRnOkSfogOvahalN6vCCQZSo7NPmeP2dzmf75vQ==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-11T07:46:27.143757"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}