@prefix this: <http://purl.org/np/RALg4jr1hCvhR9N7uzAeV4OnRh280a0qIlnqMF0ZopDPc> .
@prefix sub: <http://purl.org/np/RALg4jr1hCvhR9N7uzAeV4OnRh280a0qIlnqMF0ZopDPc#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0013600> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0013600>;
    rdf:predicate bl:treats;
    rdf:subject <https://go.drugbank.com/drugs/DB00980>;
    a rdf:Statement;
    rdfs:label "Ramelteon is a synthetic melatonin receptor agonist with high affinity for the MT1 and MT2 receptors, and is approved by the FDA for use in adults. Only few case reports have been published in children with NDDs reporting in general limited efficacy on night awakenings";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:has_population_context sub:cohort;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/28921528/>;
    bl:relation nkg:OffLabelIndication .
  
  sub:cohort rdfs:label "Children";
    bl:category bl:Cohort;
    bl:has_phenotype <http://purl.obolibrary.org/obo/MONDO_0100038> .
  
  <https://go.drugbank.com/drugs/DB00980> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "JgxMRWedTOozzP8ZSOKUKZqbwJjQmjkbhdk/7KNBz524L2GvPFt2UPqhcePuduTeF5H1JrSKNPtVZ/NWGdddtTgv/wIGlERUo78wFHbLHqmJYxPdmZe7IYcQydUFle6k7x0IcV24+ttS8vIx+gtZi3kX6DBto+dLN/Kw7KIMDaY=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-05-19T20:26:01.809+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-7641-6446;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg> .
}