. . . . . "Duloxetine" . . . "Migraine (disorder)" . . . . . . "Although antidepressants are not the first-line prophylactic strategy for patients with migraine, several clinical trials have proven their effectiveness in the treatment of migraine and related headache disorders (Koch and Jurgens, 2009). Especially TCAs: amitriptyline (Couch and Hassanein, 1979; Jackson et al., 2010; Kalita et al., 2013) and nortriptyline (Holroyd et al., 2001; Jackson et al., 2010) have the best evidence for use in migraine prevention. When amitriptyline is not tolerated by patients, treatment is continued with nortriptyline (Burch, 2019)." . . . . . . . "Adults" . . . "RSA" . "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" . "UxXGS53mfYIURlEmndw2DKWYjT7pa58dtb44XMoBYWXBe2PSwBLhFSZ9alZpuD4YjQxPirJp/6mrr7MLxq/33GvsOCHQMYT6lDt033PyBEwBmUbKZQodf2jMTR4DDkcerUr+AWRHwOZdbo5NCS2pjxL8DNT8aVItfasEIApAeOQ=" . . "2022-09-16T11:49:01.076661"^^ . . . "2.3.0" .