. . . . . . . "[Thus, we demonstrated (i) inflammation and plasma TNF-? concentrations were significantly reduced in MRL/lpr mice treated with MTX at 18 HALO, the time when TNF-? mRNA level began to increase; and (ii) MTX bedtime chronotherapy was safe, markedly reduced disease activity, and improved the functional capacity of RA patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:16:48+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .