. . . . . . . "[In this study, we investigated genes that are regulated in human colorectal cancer and by the L1-NF-?B pathway that has been implicated in liver metastasis. c-Kit was the most highly suppressed gene in both colorectal cancer tissue and the L1-NF-?B pathway. c-Kit suppression that resulted from L1-mediated signaling relied upon NF-?B, which directly inhibited the transcription of SP1, a major activator of the c-Kit gene promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:59+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .