@prefix this: <http://purl.org/np/RA8AXz5jnk5caKG-RnOT39_RD_WmPG4chQc2cBoiIzQ_U> .
@prefix sub: <http://purl.org/np/RA8AXz5jnk5caKG-RnOT39_RD_WmPG4chQc2cBoiIzQ_U#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix eco: <http://purl.obolibrary.org/obo/ECO_> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  eco:0000006 rdfs:label "experimental evidence" .
  eco:0000180 rdfs:label "clinical study evidence" .
  eco:0000204 rdfs:label "author statement" .
  eco:0000205 rdfs:label "curator inference" .
  eco:0000362 rdfs:label "computational inference" .
  eco:0005548 rdfs:label "biological system reconstruction evidence based on inference from background scientific knowledge" .
  eco:0006152 rdfs:label "medical practitioner statement evidence" .
  eco:0006153 rdfs:label "self-reported individual's statement evidence" .
  eco:0007672 rdfs:label "computational evidence" .
  sub:assertion a nt:AssertionTemplate ;
    rdfs:label "Defining a biomedical association with its context" ;
    nt:hasStatement sub:st00 , sub:st01 , sub:st02 , sub:st03 , sub:st04 , sub:st05 , sub:st06 , sub:st07 , sub:st08 , sub:st09 , sub:st10 , sub:st11 , sub:st12 , sub:st13 , sub:st14 , sub:st15 , sub:st16 , sub:st17 , sub:st18 , sub:st19 .
  sub:association a nt:LocalResource ;
    rdfs:label "This association" .
  sub:associationPredicate a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the association predicate in the BioLink model" ;
    nt:possibleValue bl:affects , bl:correlated_with , bl:interacts_with , bl:treated_by , bl:treats ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:associationRelation a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the relation between the 2 concepts of the association from RO (e.g. interacts with)" ;
    nt:possibleValuesFromApi "https://www.ebi.ac.uk/ols/api/select?ontology=ro&q=" .
  sub:associationType a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the association class from the BioLink model" ;
    nt:possibleValue bl:Association , bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation , bl:ChemicalToGeneAssociation , bl:ChemicalToPathwayAssociation , bl:GeneToDiseaseAssociation , bl:PairwiseGeneToGeneInteraction ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:evidencetype a nt:GuidedChoicePlaceholder ;
    rdfs:label "add the evidence code from the Evidence Code Ontology (ECO) here" ;
    nt:possibleValue eco:0000000 , eco:0000006 , eco:0000180 , eco:0000204 , eco:0000205 , eco:0000362 , eco:0005548 , eco:0006152 , eco:0006153 , eco:0007672 ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=ECO&q=" .
  sub:hasDrug1 a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the drugs used by this target group from Translator NameResolution API" ;
    nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
  sub:hasDrug2 a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the drugs used by this target group from Translator NameResolution API" ;
    nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
  sub:hasPhenotype a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide a URI for the specific phenotype of the target group  from Translator NameResolution API" ;
    nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
  sub:lifeStage a nt:LocalResource ;
    rdfs:label "The target group life stage" .
  sub:lifeStageName a nt:LiteralPlaceholder ;
    rdfs:label "describe the life stage or age of the target group (e.g. Adults, 18-40)" .
  sub:negated a nt:RestrictedChoicePlaceholder ;
    nt:possibleValue xsd:false , xsd:true .
  sub:object a nt:GuidedChoicePlaceholder ;
    rdfs:label "target biomedical entity from Translator NameResolution API" ;
    nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
  sub:objectType a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the object class in the BioLink model" ;
    nt:possibleValue bl:ChemicalSubstance , bl:Disease , bl:Drug , bl:Gene , bl:PhenotypicFeature , bl:Protein ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:providedBy a nt:LiteralPlaceholder ;
    rdfs:label "add the identifier of the dataset or agent providing the associations" .
  sub:publication a nt:UriPlaceholder ;
    rdfs:label "add the URI of a publication supporting this association (doi, PubMed, article URL, etc)" .
  sub:readableassertion a nt:LiteralPlaceholder ;
    rdfs:label "describe the assertion concisely (e.g. tylenol treats pain in adults patients)" .
  sub:st00 rdf:object sub:readableassertion ;
    rdf:predicate rdfs:label ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 1 .
  sub:st01 rdf:object sub:subject ;
    rdf:predicate rdf:subject ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st02 rdf:object sub:subjectType ;
    rdf:predicate bl:category ;
    rdf:subject sub:subject ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st03 rdf:object sub:object ;
    rdf:predicate rdf:object ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 4 .
  sub:st04 rdf:object sub:objectType ;
    rdf:predicate bl:category ;
    rdf:subject sub:object ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st05 rdf:object sub:associationType ;
    rdf:predicate bl:association_type ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 0 .
  sub:st06 rdf:object sub:associationRelation ;
    rdf:predicate bl:relation ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 1 .
  sub:st07 rdf:object sub:associationPredicate ;
    rdf:predicate rdf:predicate ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 1 .
  sub:st08 rdf:object sub:negated ;
    rdf:predicate bl:negated ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 6 .
  sub:st09 rdf:object sub:providedBy ;
    rdf:predicate bl:provided_by ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 7 .
  sub:st10 rdf:object sub:publication ;
    rdf:predicate bl:publications ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 8 .
  sub:st11 rdf:object sub:lifeStage ;
    rdf:predicate bl:stage_qualifier ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st12 rdf:object bl:LifeStage ;
    rdf:predicate rdf:type ;
    rdf:subject sub:lifeStage ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st13 rdf:object sub:lifeStageName ;
    rdf:predicate rdfs:label ;
    rdf:subject sub:lifeStage ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st14 rdf:object sub:targetgroup ;
    rdf:predicate bl:has_evidence ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 12 .
  sub:st15 rdf:object sub:evidencetype ;
    rdf:predicate rdf:type ;
    rdf:subject sub:targetgroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 12 .
  sub:st16 rdf:object sub:hasPhenotype ;
    rdf:predicate bl:has_phenotype ;
    rdf:subject sub:targetgroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 12 .
  sub:st17 rdf:object sub:hasDrug1 ;
    rdf:predicate bl:has_drug ;
    rdf:subject sub:targetgroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 15 .
  sub:st18 rdf:object sub:hasDrug2 ;
    rdf:predicate bl:has_drug ;
    rdf:subject sub:targetgroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 16 .
  sub:st19 rdf:object bl:EvidenceType ;
    rdf:predicate bl:category ;
    rdf:subject sub:targetgroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 12 .
  sub:st20 rdf:object rdf:Statement ;
    rdf:predicate rdf:type ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 13 .
  sub:subject a nt:GuidedChoicePlaceholder ;
    rdfs:label "source biomedical entity from Translator NameResolution API" ;
    nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
  sub:subjectType a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the subject class in the BioLink model" ;
    nt:possibleValue bl:ChemicalSubstance , bl:Disease , bl:Drug , bl:Gene , bl:PhenotypicFeature , bl:Protein ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:targetgroup a nt:LocalResource ;
    rdfs:label "The target group evidence" .
  rdf:Statement rdfs:label "association Statement" .
  rdf:object rdfs:label "has object" .
  rdf:predicate rdfs:label "has predicate" .
  rdf:subject rdfs:label "has subject" .
  rdf:type rdfs:label "has type" .
  rdfs:label rdfs:label "has label" .
  xsd:false rdfs:label "false" .
  xsd:true rdfs:label "true" .
  bl:EvidenceType rdfs:label "EvidenceType" .
  bl:association_type rdfs:label "has BioLink type" .
  bl:category rdfs:label "is in biolink category" .
  bl:description rdfs:label "is described by" .
  bl:has_drug rdfs:label "uses drug" .
  bl:has_phenotype rdfs:label "has phenotype" .
  bl:id rdfs:label "has id" .
  bl:negated rdfs:label "is negated" .
  bl:provided_by rdfs:label "is provided by" .
  bl:publications rdfs:label "has publications" .
  bl:qualifiers rdfs:label "is qualified by" .
  bl:relation rdfs:label "has relation" .
  bl:stage_qualifier rdfs:label "is qualified by life stage" .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0003-4727-9435 .
}
sub:pubinfo {
  npx:supersedes <http://purl.org/np/RAoHhGlSvD_vInhgYfbJWU-X2ugBLgdGh301xYd1_7ySw> ""^^xsd:integer .
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
    npx:hasSignature "Slo833eQBOoghp5uR6sWjAZkoMByv1Z4RmqyhJXOfyYU37useNaSllKQ5xG8L/ld7u8ypm+kTQxDA25SPB97uSFOlmigSlWvm/4s19jpVbGPKt3gPqNHymISTsCImCVxIf6ZeDdL9qXQv+Nasu80ESU6x/3J7you7qzPhpzUkYY=" ;
    npx:hasSignatureTarget this: .
  this: dct:created "2020-11-20T10:00:00+01:00"^^xsd:dateTime ;
    dct:creator orcid:0000-0003-4727-9435 .
}