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@prefix sub: <http://purl.org/np/RA2plrcTZr-bw8is5G8vCpsoHzxFXJFKjAuo8nL9hW8aE#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://identifiers.org/pubchem.compound/441308> a biolink:ChemicalEntity;
    rdfs:label "Metoprolol tartrate";
    biolink:category biolink:ChemicalEntity .
  
  umls:C1306577 a biolink:OrganismTaxon;
    rdfs:label "patient";
    biolink:category biolink:OrganismTaxon .
  
  <http://purl.obolibrary.org/obo/CHEBI_35674> a biolink:ChemicalEntity;
    rdfs:label " antihypertensive agents.";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/MONDO_0005044> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "hypertension";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/NCIT_C50646> a biolink:NamedEntity;
    rdfs:label "CONTRAINDICATIONS";
    biolink:category biolink:NamedEntity .
  
  sub:_1 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005044>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/441308>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_2 rdf:object <http://www.ebi.ac.uk/efo/EFO_0003913>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/441308>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_3 rdf:object <file:///app/>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/441308>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  sub:_4 rdf:object <http://purl.obolibrary.org/obo/CHEBI_35674>;
    rdf:predicate biolink:interacts_with;
    rdf:subject <http://identifiers.org/pubchem.compound/441308>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5b8fb137-848b-45fd-9107-a6db5a675360> .
  
  <http://www.ebi.ac.uk/efo/EFO_0003913> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "angina pectoris";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-10T16:25:11.733205"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Metoprolol tartrate tablets are indicated for the treatment of hypertension and angina pectoris. They may be used alone or in combination with other antihypertensive agents. Treatment can be initiated as soon as the patient's clinical condition allows (see DOSAGE AND ADMINISTRATION, CONTRAINDICATIONS, and WARNINGS). Treatment can begin within 3 to 10 days of the acute event." .
  
  biolink: pav:version "2.3.0" .
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sub:pubInfo {
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}