. . . . . . . "[In rare patients with autosomal dominant, early-onset Alzheimer's disease (AD), pathogenic mutations in the genes encoding ?-amyloid precursor protein, and the ?-secretase-complex components presenilin-1 and presenilin-2 appear to result in ?-amyloid (A?) overproduction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:42+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .