@prefix this: <http://purl.org/np/RA1mFMDNtnDJcNuxY-I2uLbZZwMf6HW2ZiZ1fInDzI2dE> .
@prefix sub: <http://purl.org/np/RA1mFMDNtnDJcNuxY-I2uLbZZwMf6HW2ZiZ1fInDzI2dE#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_9164> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_9164>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/drugbank:DB00710>;
    a rdf:Statement;
    rdfs:label "\"Ibandronate sodium is contraindicated in patients with the following conditions: * Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia  (see Warnings and Precautions [ 5.1 * Inability to stand or sit upright for at least 60 minutes  (see Dosage and Administration [2.2], and Warnings and Precautions [ 5.1 * Hypocalcemia  (see Warnings and Precautions [ 5.2 * Known hypersensitivity to ibandronate sodium tablets or to any of its excipients. Cases of anaphylaxis have been reported.  (see Adverse Reactions [6.2]) * Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia ( 4 5.1 * Inability to stand or sit upright for at least 60 minutes ( 4 5.1 * Hypocalcemia ( 4 * Hypersensitivity to ibandronate sodium ( 4\"";
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:relation schema:MedicalContraindication .
  
  <https://identifiers.org/drugbank:DB00710> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "MFzXRymh5xnNhIyPkeoxpJhsB/RRDKYqBSgRqV3YfoJKuhxKq0WVVI2rHbxONGCRU/gBC9c37pW8eAsjH8n1rNPPOHcdox6nubjqva1jJ/ZGu1S7FxERJf/ef1rrLe7nyv/Fn/m5uA5GwupuIsTMTUxSaYwzJa0uLudaSucFfAk=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-08-23T19:06:18.192+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}