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[We show that the common activating epidermal growth factor receptor (EGFR) mutation (EGFRvIII) stimulates mTORC2 kinase activity, which is partially suppressed by PTEN. mTORC2 signaling promotes GBM growth and survival and activates NF-?B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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