@prefix this: <http://purl.org/np/RA-nAPMTi2uiDinyL7dKUfxmSP0ZpViDtRZV8QbsPmlwo> .
@prefix sub: <http://purl.org/np/RA-nAPMTi2uiDinyL7dKUfxmSP0ZpViDtRZV8QbsPmlwo#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://identifiers.org/pubchem.compound/5152> a biolink:ChemicalEntity;
    rdfs:label "Salmeterol";
    biolink:category biolink:ChemicalEntity .
  
  umls:C0004096 a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "asthma";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/CHEBI_50858> a biolink:ChemicalEntity;
    rdfs:label "corticosteroid";
    biolink:category biolink:ChemicalEntity .
  
  <http://purl.obolibrary.org/obo/MONDO_0001358> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "bronchospasm";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005002> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "airflow obstruction", "chronic obstructive pulmonary disease";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:object <http://purl.obolibrary.org/obo/CHEBI_50858>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/5152>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_2 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_50858>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_3 rdf:object <http://purl.obolibrary.org/obo/CHEBI_50858>;
    rdf:predicate biolink:treated_by;
    rdf:subject umls:C0004096;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_4 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/5152>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_5 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_50858>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_6 rdf:object umls:C0004096;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/5152>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_7 rdf:object <http://purl.obolibrary.org/obo/MONDO_0001358>;
    rdf:predicate biolink:positively_correlated_with;
    rdf:subject <http://purl.obolibrary.org/obo/CHEBI_50858>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_8 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005002>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/5152>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
  
  sub:_9 rdf:object <http://purl.obolibrary.org/obo/MONDO_0001358>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/5152>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0c3eeb6-8a75-0b20-2008-396e63cddcdb> .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-13T13:38:37.240623"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom " Salmeterol is indicated in the treatment of asthma with an inhaled corticosteroid, prevention of exercise induced bronchospasm, and maintenance of airflow obstruction and prevention of exacerbations of chronic obstructive pulmonary disease. The drug has been shown to be effective in asthma, asthma and other respiratory conditions in the U.S. as well as asthma sufferers in the United States and Canada." .
  
  biolink: pav:version "2.3.0" .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEApdULbl+/+pkVlq0fAzWmzfgIb+XMuQPKHMDVzUTWCZBjLfzORll42ptr52e4w7tTYkUKrBsQbx8lkjZWAlWiyh+xIK0oLFSdYRSt63kgiyRYBUOR+spcgmofb7f6JyftArPVTKhsWOMt/mcyNG9qc3lw8B/xuPmLteUWO33xWhfXQreTw1lsGUkZ1j4cB4X9HIuI20ktLYLCXaBauNHEJZ4qp6/Q2ATsJcw8tg7aRmFKXhrjM9maZ2+0cMg0Jpmn2UnDlPKXEA6Qq+qnvvQt8KFjIzP9FTMyvrWl8tTd0NCmS9VpooZJQ8We1lGMPXg5bMbe/bVkTf70fbFMf0RKrQIDAQAB";
    npx:hasSignature "YAm6Qyme6GEFHryi6RP3znSWkOvSKDtYE/Qc9f9nrur6BZFE0izgOF38Ufd1OU0HI4myE2Ts9R1+02BOk1xPyqJM8417+nXrH3pHOZRO5yJikLcaGq1uSnKqVQgV+ucQ0WgBw9oqmO0ErV6c6kf3G1XYwfq1wlHSqHL/th3CLmDDlOFrKSecrFkpArqvNuKj9AXgW6li1Frefrl73KJHN7aeELP3obk6vpeuWib9XxoOT2qDUOsQgjObMukwc9Vjy7D/7BqSRdpbTW1fxjKne4qcplmNiPHIm5gqMgLk57srmiKkJmm9FVTtB6dDzY2AwRtkaUGsFEKDE/mZzGTAmg==";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2022-10-13T13:38:37.240623"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}