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@prefix sub: <http://purl.org/np/RA-cg1AjOtG_RpLurF1Z9l0X6906nTx6dw7XibZKVkMOY#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
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    rdfs:label "norepinephrine";
    biolink:category biolink:ChemicalEntity .
  
  <http://identifiers.org/pubchem.compound/681> a biolink:ChemicalEntity;
    rdfs:label "dopamine";
    biolink:category biolink:ChemicalEntity .
  
  umls:C1299487 a biolink:OrganismTaxon;
    rdfs:label "patients";
    biolink:category biolink:OrganismTaxon .
  
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    rdfs:label "septic shock";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/MONDO_0005468> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "hypotension";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  <http://purl.obolibrary.org/obo/NCIT_C50671> a biolink:DiseaseOrPhenotypicFeature;
    rdfs:label "neurogenic shock";
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  
  sub:_1 rdf:object <http://purl.obolibrary.org/obo/MONDO_0001881>;
    rdf:predicate biolink:treats;
    rdf:subject <http://identifiers.org/pubchem.compound/439260>;
    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
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    a biolink:Association;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=33a147be-233a-40e8-a55e-e40936e28db0> .
  
  sub:_3 rdf:predicate biolink:treats;
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    biolink:aggregator_knowledge_source infores:knowledge-collaboratory;
    biolink:category biolink:Association;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=33a147be-233a-40e8-a55e-e40936e28db0> .
  
  sub:_4 rdf:object <http://purl.obolibrary.org/obo/NCIT_C50671>;
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    biolink:category biolink:Association;
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}

sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-13T13:31:09.797453"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-3668-2627;
    prov:wasQuotedFrom "norepinephrine is Mainly used to treat patients in vasodilatory shock states such as septic shock and neurogenic shock. Also used as a vasopressor medication for patients with critical hypotension. Has shown a survival benefit over dopamine over dopamine. Has been shown to be a better alternative to dopamine for a better survival benefit in patients with severe hypotension or with critical hypotension at risk of septic shock." .
  
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